Treatment of haemophilia A in Tunisia: efficacy and inhibitor study
Mliki, M.; Abdelkafi, S.; Bouslama, M.; Zaïer, M.; Mahjoub, T.; Kortas, M.; Ghachem, L.; Yacoub, S.; Houissa, B. · Zeitschrift für Orthopädie und Unfallchirurgie · 2003 · Heft 03 · S. 144 bis 148
Bibliografische Angaben
Zusammenfassung
SummaryCryoprecipitate is the principal type of factor VIII (FVIII) concentrate used for treating haemophilia A in Tunisia. Allergic reactions, viral transmission, and inhibitor formation remain the most serious complications of FVIII therapy. The aims of the study presented here were to evaluate the efficacy of FVIII therapy, to investigate the inhibitor prevalence, and the factors which may affect inhibitor formation in our haemophilia A patients. Plasma samples were screened for FVIII inhibitors by the Bethesda method. 30 minutes FVIII recovery was also determined for each patient. In this prospective study,…