Use of Vonicog Alpha and Acquired von Willebrand Syndrome, a New Approach: A Case Report
Blandinières, A.; Combe, S.; Chanson, N.; Lambotte, O.; Lavenu-Bombled, C. · Zeitschrift für Orthopädie und Unfallchirurgie · 2024 · Heft 3 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
AbstractTherapeutic management of acquired von Willebrand syndrome (AVWS) can be challenging, particularly in cases of AVWS associated with monoclonal IgM such as Waldenström macroglobulinemia (WM) where several therapeutic options may be ineffective. Here, we describe the case of an 88-year-old patient who developed AVWS during follow-up for WM. The presence of a severe bleeding symptomatology not controlled by several therapies (plasma-derived von Willebrand factor, plasmapheresis) led us to introduce a supplementation with recombinant von Willebrand factor, vonicog α (Veyvondi, Takeda, Japan), starting at a d…
