Digenic Inheritance of PROC and SERPINC1 Mutations Contributes to Multiple Sites Venous Thrombosis
Li, X.; Zhu, J.; lv, F.; Ma, W.; Zhou, W.; Zhang, W. · Zeitschrift für Orthopädie und Unfallchirurgie · 2024 · Heft 06 · S. 472 bis 477
Bibliografische Angaben
Zusammenfassung
AbstractVenous thromboembolism (VTE) represents a worldwide health challenge, impacting millions of people each year. The genesis of venous thrombosis is influenced in part by genetic components. Hereditary thrombosis is described as a genetically determined susceptibility to VTE. In the present study, a male patient was referred to our department presenting with multiple venous thrombosis events in different locations. Given a lack of identifiable risk factors, we aimed to investigate the possible genetic factor underlying venous thrombosis. Whole-exome sequencing was employed to examine genes linked to inherit…
