In Silico Hemostasis Modeling and Prediction
Nechipurenko, D.-Y.; Shibeko, A.-M.; Sveshnikova, A.-N.; Panteleev, M.-A. · Zeitschrift für Orthopädie und Unfallchirurgie · 2020 · Heft 04 · S. 524 bis 535
Bibliografische Angaben
Zusammenfassung
AbstractComputational physiology, i.e., reproduction of physiological (and, by extension, pathophysiological) processes in silico, could be considered one of the major goals in computational biology. One might use computers to simulate molecular interactions, enzyme kinetics, gene expression, or whole networks of biochemical reactions, but it is (patho)physiological meaning that is usually the meaningful goal of the research even when a single enzyme is its subject. Although exponential rise in the use of computational and mathematical models in the field of hemostasis and thrombosis began in the 1980s (first fo…
