Calibrated automated thrombin generation in paediatric patients with inflammatory bowel disease
Bernhard, H.; Deutschmann, A.; Leschnik, B.; Novak, M.; Hauer, A.; Haidl, H.; Rosenkranz, A.; Muntean, W. · Zeitschrift für Orthopädie und Unfallchirurgie · 2009 · Heft S 01 · S. S90-S93
Bibliografische Angaben
Zusammenfassung
SummaryIn adults, inflammatory bowel disease (IBD) is associated with an increased risk of thromboembolic complications. The pathogenesis of IBD is not really clear and a high thrombin activity might contribute to disease progression. We wanted to see whether children with IBD have a higher thrombin generation (TG). Patients, material, methods: Plasma samples were collected of 20 patients with IBD and of 60 healthy controls (age range from 10 to 19). TG was measured by means of Calibrated automated thrombography (CAT). The disease activity was estimated, using the Pediatric Crohn‘s Disease Activity Index (PCDAI)…
