Analysis of platelet function and dysfunction
Jurk, K. · Zeitschrift für Orthopädie und Unfallchirurgie · 2015 · Heft 01 · S. 60 bis 72
Bibliografische Angaben
Zusammenfassung
SummaryAlthough platelets act as central players of haemostasis only their cross-talk with other blood cells, plasma factors and the vascular compartment enables the formation of a stable thrombus. Multiple activation processes and complex signalling networks are responsible for appropriate platelet function. Thus, a variety of platelet function tests are available for platelet research and diagnosis of platelet dysfunction. However, universal platelet function tests that are sensitive to all platelet function defects do not exist and therefore diagnostic algorithms for suspected platelet function disorders are…