Current trends in PCO Research

It is now 10 years since the introduction of the Acrysof IOL which introduced the first possibility to significantly reducing PCO. This presentation looks at why Acrysof IOLs reduce PCO, the effect of optic material on PCO and why some patients still develop PCO. Mathematical modelling suggests that a square edge IOL would exert more pressure on the posterior capsule than a round edge IOL and we believe this pressure barrier is responsible for preventing cell growth on to the posterior capsule rather than cell inhibition. This barrier will be enhanced by posterior vaulting of the haptic, capsular – IOL adhesion…