Rectal bleeding from colon endometriosis may be difficult to differentiate from that of colon cancer

The gastrointestinal tract is the most common site extrapelvic endometriosis. Prevalence is 5–15% in the female population. The rectum and sigmoid colon are the most commonly involved areas (75–90%), it appears in the distal ileum in 2–16% and in the appendix in 3–18%. The serosa and the muscular propria are usually involved, the mucosa is very rarely affected. The colon endometriosis is presented with different symptoms which can be cyclical in about 40% of patients. The clinical, radiological and endoscopic picture may refer to neoplasm, IBD, postirradiation colitis, ischemic colitis, diverticular disease and…