Transcranial Sonography (TCS) of Brain Parenchyma in Corticobasal Degeneration

Introduction: TCS of brain parenchyma has recently been demonstrated to be able to detect characteristic ultrasound features in various movement disorders. Aim of the study was to evaluate the echo pattern of parenchymal structures in patients with corticobasal degeneration (CBD). Methods: TCS was performed in 8 patients (mean age 67±8 years) who met the clinical diagnostic criteria for CBD (Litvan et al., 1997) and 20 age-matched non-parkinsonian controls using a standardized protocol. The signal intensity (echogenicity) of the substantia nigra (SN) and the thalamus was assessed bilaterally and the width of the…