MRT-Based Morphometry: Confounding Parameters and Sensitivity of Methods

In neurobiological applications, morphometry aims at a description of brain structure from imaging modalities in terms of size, shape, and texture. Such measures may be evaluated by automated statistical techniques and analyzed together with other clinical and experimental parameters. Thereby, morphometry offers promising approaches for an in vivo characterization of many neurological or psychiatric pathologies. A survey of the recent publications only allusively reflects this attractiveness of MR-based morphometry: published findings are heterogeneous, partly contradictory and not always plausible in terms of k…