Missing SMA Activation in Self-Initiated Movements after Chronic Prefrontal Traumatic Brain Injury: An Event-Related fMRI Study

Objective: In former studies, we found the Bereitschaftspotential, an EEG component related to the preparation of self-initiated movements, to be reduced in the acute stage after prefrontal TBI (Wiese et al., Clin Neurophysiol, 2004). However, in the temporal course after the injury a functional reorganization was observed, which resulted in a lateralization of this normally symmetrically distributed component towards the hemisphere contralateral to the movement one year after TBI (Wiese et al., Clin Neurophysiol, accepted). Since the localization of brain regions generating these potentials was not possible, th…