Cholesterol binding antibodies in primary biliary cirrhosis?
T Csak, A Folhoffer, A Horvath, A Bíró, P Lakatos, J Osztovits, T Toth, A Habior, G Bekő, I Tornai, I Karádi, G Füst, F Szalay · Zeitschrift für Gastroenterologie · 2005 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Naturally occurring autoantibodies to cholesterol in humans have been described. Anti-cholesterol antibodies (ACHA) are natural antibodies against the 3beta-OH group of cholesterol. High level ACHA was reported in SLE, HIV and hepatitis C infected patients. ACHA is subject of research in atherosclerosis. Hypercholesterolaemia is common in PBC, although its clinical significance is not fully clarified. We aimed to investigate ACHA and its correlation with lipid and clinical parameters in patients with PBC. Subjects and Methods: 109 patients with PBC (108F/1M, age: 58.74±9.6 years, each AMA positive) a…