The effect of resveratrol on cholecystokinin-octapeptide-induced experimental pancreatitis in rats

Resveratrol is a phytoalexin that reaches high concentrations in the skin of grapes and in red wine. The antioxidant, anti-inflammatory and also anti-cancer effects of the substance were shown in several in vivo and in vitro experiments. Moreover, this dietary component is thought to be responsible for the so-called “French paradox“, describing the association of red wine consumption and reduced mortality of breast cancer and coronary heart disease. Aim: The aim of this study was to test the effect of resveratrol on the cholecystokinine-octapeptide (CCK 8) induced acute pancreatitis (AP) model in rats. Methods:…