Sequential activation of the motor network in single subjects

The spatially and temporally separated contribution of primary motor, premotor and prefrontal areas in delayed movements can be illustrated with fMRI in group (n=10) analysis (Hülsmann et al., NeuroImage 2003, 20: 1485–1492). In order to study the impact of heterogeneous lesions on the timing of cortical motor control (e.g. in recovery after stroke), reliable consistent results on a single subject basis are essential. The aim of this study was to prove that detection of sequential activation in single subjects is feasible. Methods: We studied a right-handed woman of 30 years with event-related fMRI during a visu…