Determination of language lateralization with fMRI – Introduction of a new paradigm with auditory stimulation

Background: Functional magnetic resonance imaging (fMRI) has been proven to be a feasible method for the determination of language lateralization both in clinical diagnostics and in neuroscientific research. Here we present a new paradigm with auditory stimulation with a low task difficulty that is also applicable in children, subjects with cognitive limitations and subjects with visual disturbances. Methods: During 13 minutes of fMRI scanning, subjects listen to a story presented via headphones. The task is to react to target stimuli (animals) by button presses. This language processing condition is alternated…