CareLit Fachartikel

Direct Oral Anticoagulants in Atrial Fibrillation: Practical Considerations and Remaining Issues

Jan Beyer-Westendorf · Zeitschrift für Orthopädie und Unfallchirurgie · 2021 · Heft 01 · S. 035-041

Dokument
805601
CareLit-ID
Jahr
2021
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Orthopädie und Unfallchirurgie
Autor:innen
Jan Beyer-Westendorf
Ausgabe
Heft 01 / 2021
Jahrgang 41
Seiten
035-041
Erschienen: 2021-02-01 00:00:00
ISSN
0720-9355
DOI
10.1055/a-1329-2430

Zusammenfassung

AbstractPreventing thromboembolic events, while minimizing bleeding risks, remains challenging when managing patients with atrial fibrillation. Despite large and successful trial programs, several clinical concerns remain which commonly relate to fears of over- or underexposure to drugs and unfavorable outcomes. After a short summary of the main phase III trial findings, this short review discusses the evidence and clinical relevance of common clinical concerns (correct direct oral anticoagulant [DOAC] dosing; DOAC in moderate-to-severe renal impairment; and the relevance of fasting, nasogastric tube feeding, or…

Schlagworte

direct oral anticoagulants atrial fibrillation stroke Antidotes After Anticoagulants Zeitschrift für Orthopädie und Unfallchirurgie