CareLit Fachartikel

Thrombotic Thrombocytopenic Purpura: When Basic Science Meets Clinical Research

Adrien Picod, Raïda Bouzid, Agnès Veyradier, Paul Coppo · Zeitschrift für Orthopädie und Unfallchirurgie · 2021 · Heft 04 · S. 283-293

Dokument
805702
CareLit-ID
Jahr
2021
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Orthopädie und Unfallchirurgie
Autor:innen
Adrien Picod, Raïda Bouzid, Agnès Veyradier, Paul Coppo
Ausgabe
Heft 04 / 2021
Jahrgang 41
Seiten
283-293
Erschienen: 2021-08-01 00:00:00
ISSN
0720-9355
DOI
10.1055/a-1332-3066

Zusammenfassung

AbstractThe therapeutic landscape of thrombotic thrombocytopenic purpura (TTP) is rapidly changing with the recent availability of new targeted therapies. This progressive shift from empiricism to pathophysiology-based treatments reflects an intensive interaction between the continuous findings in the field of basic science and an efficient collaborative clinical research and represents a convincing example of the strength of translational medicine. Despite the rarity of TTP, national and international efforts could circumvent this limitation and shed light on the epidemiology, clinical presentation, prognosis,…

Schlagworte

plasma exchange thrombotic thrombocytopenic purpura thrombotic microangiopathy rituximab caplacizumab ADAMTS13 Clinical Therapeutic Changing Recent Findings Long-Term Outcome Thrombotic Thrombocytopenic Purpura