Are signs of ocular tilt reaction in patients with cerebellar lesions mediated by the dentate nucleus?

Objective: A sensitive clinical sign of a vestibular tone imbalance in the roll plane is the ocular tilt reaction (OTR), a combination of head and perceptual tilts, vertical divergence of the eyes (skew deviation, SD) and ocular torsion (OT) in the same direction. While these signs are regularly seen in patients with acute unilateral brainstem lesions affecting central vestibular pathways, only a few case studies are available on its occurrence in patients with cerebellar lesions[1,2]. Thus, the question arises whether contra- and/or ipsiversive tilts of the perceived vertical and the other signs of OTR, such as…