A systematic literature review to specify functioning in individuals with Multiple Sclerosis

Objective: To explore aspects of functioning and health reported in studies including individuals with Multiple Sclerosis (MS). The specific aims were (1) to identify parameters focusing on individuals with MS reported in studies and (2) to identify and quantify the concepts contained in these parameters using the International Classification of Functioning, Disability and Health (ICF) as a reference. Methods: Electronic systematic searches in MEDLINE, EMBASE, PSYCINFO, CINAHL and CENTRAL from 2002 to 2007 were performed using the search terms 'multiple sclerosis', 'demyelinating diseases' and 'definite MS'. Stu…