Methylene blue aided cholangioscopy for the detection of neoplastic biliary lesions

Introduction: Patients with biliary malignancies do have a poor prognosis. Aim of the current feasibility study was to investigate the value of methylene blue aided cholangioscopy for the early detection of neoplastic biliary lesions. Methods: Patients with suspected biliary lesions (ultrasonography or MRT) or long standing primary sclerosing cholangitis (PSC) were scheduled for ERCP with subsequent cholangioscopy (FCP-9P) using the mother and baby technique. The intra- and extrahepatic biliary tree was inspected with cholangioscopy and subsequently stained with 20ml of methylene blue at a final concentration of…