Management and course of histological verified cervical carcinoma in situ during pregnancy

Aims: To study the rate of regression and progression into invasive disease of patients with histological proven carcinoma in situ of the uterine cervix during pregnancy Methods: Prospective observation of all pregnant women with biopsy-proven carcinoma in situ of the uterine cervix, gained by colposcopic guided biopsy from 1996–2004 and correlation with the route of delivery and cytologic and histologic postpartum findings. Results: 83 patients with histological verified carcinoma in situ during pregnancy were treated conservative. Two patients were lost to follow up, one patient had an abortion and three are s…