Stimulation of subthalamic fibre tracts reduces dyskinesias in STN-DBS

Objective: To describe the efficacy of stimulation within the subthalamic white matter for reducing dyskinesias associated with subthalamic deep brain stimulation (STN-DBS) Aims: In some PD-patients, the postoperative management following STN-DBS is complicated by pharmacologically intractable dyskinesias. Here we report three patients, in whom additional stimulation of the most proximal contact led to significant reduction of dyskinesias. Methods: The clinical dyskinesia rating scale (CDRS, max 28) was used to assess dyskinesias before and three months after stimulation of the most proximal contact of the quadr…