Genetics in glaucoma

This talk will review five areas of development in the molecular genetics of glaucoma. New families: Congenital optic nerve excavation linked to chromosome 12. Animal models of glaucoma: A potential mouse model for pseudoexfoliation glaucoma. Gene chip technology: The tremendous power for gene chips to accelerate the discovery of disease-causing genes. The availability of genetic testing. A non-profit center is available at www.carverlab.org. Currently a myocilin test can be ordered. On the horizon are CYP1B1, PITX2, FOXC1, and PAX6. Gene-directed therapy: Gene replacement Therapy based upon an understanding of…