CareLit Fachartikel
Placenta mesenchymal stem cells on a chorion scaffold as a potential osteogenic graft for peripartal bone regeneration
S Mohr, BC Portmann-Lanz, A Schoeberlein, R Sager, DV Surbek · Geburtshilfe und Frauenheilkunde · 2008 · Heft 09
Dokument
808966
CareLit-ID
Jahr
2008
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
1 Objective To manufacture a three dimensional, biodegradable and stem cell-loaded composite graft from placental components for site-specific perinatal repair of bone defects in newborns suffering from genetic skeletal dysplasias. 2 Study Design We manufactured a scaffold from human chorion membrane by removing cellular components from the chorionic reticular layer enzymatically and mechanically. That acellular scaffold served as a support material for placental mesenchymal stem cell (MSC) outgrowth in that we cultured human MSCs derived from either first trimester chorionic villi or term chorion membrane on it…
Schlagworte
MSC
chorion
fetal
scaffold
tissue-engineering
Geburtshilfe und Frauenheilkunde
