Functional neuroanatomy of CCK-4 induced panic attacks: indications for specifically anxiety-related brain activity
G Leicht, D Eser, J Lutz, S Wenninger, V Kirsch, C Schüle, S Karch, T Baghai, HJ Möller, O Pogarell, C Born, R Rupprecht, C Mulert · Klinische Neurophysiologie · 2009 · Heft 03
Bibliografische Angaben
Zusammenfassung
The experimental triggering of panic attacks under controlled conditions offers the possibility to examine the pathophysiological factors which form the base of panic disorders. The application of CCK-4 to release panic attacks is considered to be a safe, valid and reliable model to investigate neurobiological aspects of panic disorders. The aim of the present study was to investigate the brain activity pattern evoked by a CCK-4 induced panic attack using functional MRI and focusing on the putative involvement of the amygdala in the CCK-4 elicited anxiety response. 16 healthy male subjects were challenged with C…
