Secondary Generalization Prolonges Seizure Duration in Temporal but not in Frontal Lobe Epilepsies

Purpose: To evaluate the duration of seizures arising from the frontal and temporal lobes in order to better understand spread and inhibitory mechanisms involved. Methods: We investigated the seizure duration as measured by ictal non-invasive EEG in 233 seizures arising from the temporal and frontal lobes in 41 patients with temporal and frontal lobe epilepsies. Results: Of the 130 seizures arising from the temporal lobes 13.8%generalized secondarily, compared to 24.3% secondary generalization in 103 seizures of FLE. In TLE patients, the average duration was significantly longer in secondarily generalized seizur…