Multifocal inflammatory demyelinating neuropathy with GM-1-antibodies and central conduction failure in a marathon runner

Multifocal inflammatory demyelinating neuropathy (MIDN) is an asymmetric sensory or sensorimotor demyelinating neuropathy not fulfilling the diagnostic criteria for chronic inflammatory demyelinating polyneuropathy (CIDP) or multifocal motor neuropathy (MMN). Evidence of multifocal demyelination and conduction block in motor and sensory nerves can be demonstrated on electrophysiologic examination, patients exhibit a beneficial response to IV immunoglobulin treatment (IvIg). We report a case of a 52 year old male amateur runner with the third relapse of an asymmetric, predominantly motor weakness with some sensor…