Correlation of intelligence and human brain structure

Objective: Biological correlates of intelligence have been discussed since a long time. Structural and functional neuroimaging studies mostly reported correlation findings in frontoparietal cortical areas. However, the relationship between intelligence and ultrastructural properties of the brain has hardly been investigated. Methods: High-resolution T1-weighted magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) data sets were acquired in N=26 unrelated healthy subjects (age: 22.7±1.8 years). IQ was assessed by the HAWIE-R (Hamburg-Wechsler Intelligenztest) Scale. Voxel-wise t-statistic regressio…