Is there any effect of fetal gender on the markers of first trimester Down syndrome screening

Introduction: At present, the most effective trisomy 21-screening method is the estimate of risk combining maternal age, fetal nuchial translucence, free Beta- human-chorionic, gonadotropin (Beta HCG) and pregnancy associated plasma protein A (PAPP- A) Objective: The aim of this study was to investigate the humble effect of fetal gender in first trimester Down syndrome screening markers. Design: Retrospective study Setting: Prenatal Diagnosis Centre in a Tertiary Hospital in Lagos. Methods: In a total of n=350 pregnancies in which fetal nuchial translucency and maternal serum free beta HCG and PAPPA were perform…