Neurophysiological correlates of the subjective pain experience

The perception of pain exhibits substantial intra- and inter-individual variations. Within the brain, the subjective experience of pain is associated with a variety of neurophysiological phenomena. Specifically, high frequency γ oscillations have been related to the subjective experience of pain. Here, we further investigated the relationship between intraindividual variations of pain perception and pain-related neuronal oscillations in the human brain on a single trial level. In 18 healthy human subjects, brain activity during pain perception was recorded with a 64 channel EEG system. Using a Nd:YAP laser, 60 s…