Sensitivity of gait analysis to detect motor phenotype in pre-manifest and manifest Huntington's disease – cross-sectional results from the TRACK-HD Study
S Rohm, N Bechtel, H Beckmann, A Sturrock, S van den Bogaard, M Say, C Jauffret, JA Mills, TP Archarya, DR Langbehn, H Johnson, B Borowsky, A Durr, BR Leavitt, R Roos, JC Stout, SJ Tabrizi, B Landwehrmeyer, R Reilmann · Aktuelle Neurologie · 2009 · Heft 10
Bibliografische Angaben
Zusammenfassung
Background: Deficits in postural control and gait are well established symptoms of Huntington's Disease (HD), which contribute to falls and loss of independence. Gait impairment is currently being assessed by the Unified Huntington's Disease Rating Scale Total Motor Score (UHDRS-TMS). Previous studies have shown that the use of the GAITRite mat (www.GAITRite.com) provides additional objective and quantitative information: e.g., correlations with predicted years to onset and years since onset (Rao et al. 2008), and differences in gait measures for fallers vs. non-fallers and controls (Grimbergen et al. 2008). Obj…
