Thymoma-associated limbic encephalitis: remission after thymectomy and rituximab

We report a 59-year-old patient presenting with disorientation, memory loss and simple partial seizures with olfactory hallucinations and parasthesia in the right arm. On admission, neurological examination was normal except for marked neuropsychological impairment, mainly involving short and long-term memory. Bilateral temporal epileptic discharges were seen in the EEG. High intensity signals in the medial and anterior temporal lobes were seen on T2-weighted and FLAIR MRI images, suggestive of a limbic encephalitis. Chest-CT scan showed a tumorous mass infiltrating the pleura and the inferior lobe of the right…