A novel intravenous iron formulation for treatment of anemia in IBD: The ferinject randomized, controlled trial
S Kulnigg, V Rumyantsev, S Stoinov, V Simanenkov, E Levchenko, W Karnafel, L Chaires Garcia, G D'Haens, C Gasche · Zeitschrift für Gastroenterologie · 2007 · Heft 07
Bibliografische Angaben
Zusammenfassung
Background: Anemia is a common complication in IBD caused by various degrees of iron deficiency and anemia of chronic disease. Recently, a new parenteral iron preparation, iron carboxymaltose (FeCarb; Ferinject, Vifor Int.) was developed that can be administered iv at single and repeated high doses up to 1000mg within 15min. Aims: This study compared the efficacy (non-inferiority) and safety of FeCarb with oral ferrous sulfate (FeSulf) in reducing iron deficiency anemia in IBD. Methods: This randomized, controlled, multi-center, phase-III trial was performed in IBD patients with a hemoglobin (Hb) ≤11g/dl and a t…
