Early chronic Globus pallidus internus stimulation in paediatric and juvenile patients suffering from intractable primary dystonia

Objective: Globus pallidus internus (GPI) deep brain stimulation (DBS) offers a very effective stereotactic neurosurgical therapy for medically intractable dystonia. Although generalized dystonia is presenting mainly at young age and might be severely disabling, GPI-DBS is still usually not applied in the early course of the disease. We here present the immediate post-operative results and clinical follow for 5 paediatric/juvenile patients undergoing GPI-DBS. Methods: All patients (mean age 13 years (range 8–16 years), 3 female/2 male, 2 DYT1-positive) were suffering from intractable primary generalized dystonia…