Hippocampal abnormalities in patients with malformations of cortical development and epilepsy
G Kuchukhidze, I Unterberger, J Dobesberger, N Embacher, G Walser, E Haberlandt, F Koppelstätter, T Gotwald, H Maier, M Ortler, S Felber, E Trinka · Aktuelle Neurologie · 2007 · Heft 09
Bibliografische Angaben
Zusammenfassung
Purpose: Malformations of cortical development (MCD) represent a heterogeneous group of brain abnormalities determined by disrupted stages of neuronal development. They are increasingly recognised as a major cause for medically refractory epilepsy, focal neurological deficits and cognitive disturbances. There have been few reports on hippocampal abnormalities (HA) associated with MCD. This study aimed to identify the spectrum and frequency of HA in patients with MCD and epilepsy. Methods: We identified 137 patients (75w/62m) aged 1–74 years (mean 31 years) with MCD and epilepsy from our department database. All…
