Pre-morbid antiplatalet use is associated with larger haematoma volume and worse outcome after intracerebral haemorrhage: population-based study

Background: Premorbid oral anticoagulation is a risk factor for poor outcome following intracerebral haemorrhage (ICH). In a recent study of hospitalised patients with ICH, premorbid aspirin use also increased early mortality, possibly via early haematoma growth. We aimed to determine whether this association could be reproduced in a population-based stroke incidence study. Methods: Consecutive patients with ICH were prospectively ascertained from the Oxford Vascular Study. Data were collected on vascular risk factors and pre-morbid medication use. Patients on anticoagulation prior to the ICH were excluded. The…