„One-Stop-Shop“ ultrasound diagnosis of functional, structural and physicomechanical properties of the brachial artery

Aim: To develop and validate a single non-invasive examination of the brachial artery for simultaneous and highly accurate measurement of endothelial function, intima-media-thickness, and compliance using high resolution ultrasound. Aims: The pathogenesis of atherosclerosis comprises endothelial dysfunction, thickening as well as impaired compliance of the arterial vessel wall. Early assessment of these functional, structural and physicomechanical alterations of the vessel wall at the same site of the vascular tree has yet been hampered by the lack of highly sensitive diagnostic approaches suitable for clinical…