Accuracy of intraoperative assessment of surgical margins in breast conserving therapy of invasive breast carcinoma by frozen section: a retrospective quality control analysis

Background: The1 role of intraoperative assessment of surgical margins during breast conserving therapy (BCT) of invasive breast carcinoma (IBC) by frozen section (FS) is widely used but controversial. FS has the disadvantage that only a limited number of sections can be investigated within an acceptable amount of time and cutting of fatty tissue is difficult. The aim of this study is to compare the results of FS of BCT specimens with final histology on paraffin-embedded sections (PS). Patients and methods: 152 consecutive cases of breast specimen obtained from a single institution for FS were retrieved from the…