BRCA gene mutations in Slovenian male breast cancer patients
N Besic, B Cernivc, J De Greve, K Lokar, M Krajc, S Novaković, J Žgajnar, E Teugels · Senologie - Zeitschrift für Mammadiagnostik und -therapie · 2007 · Heft 09
Bibliografische Angaben
Zusammenfassung
Male breast cancer (MBC) is a rare disease, comprising less than 1% of breast cancer patients in Slovenia. Some inherited cases are due to the mutations of BRCA1 or BRCA2 genes. The purpose of this population-based study is to determine the prevalence of BRCA gene mutations in MBC patients in Slovenia. Records on all 142 male patients, treated for breast cancer between 1975 and 2007at the Institute of Oncology Ljubljana were retrieved. At the time of our study, 43 patients were alive, and they were proposed to take part in this study. Of them, 29 agreed to follow a genetic counseling session and 26 patients agre…