Anti-inflammatory and anti-cancer effects of the phytomedicine STW 5 (Iberogast®)
GA Bonaterra, O Kelber, R Kinscherf, U Traut, S Seitz, D Weiser, J Metz · Zeitschrift für Phytotherapie · 2008 · Heft 02
Bibliografische Angaben
Zusammenfassung
STW 5 (Iberogast®) is a phytomedicinal combination of nine herbal extracts indicated for functional gastro-intestinal diseases. As subchronic inflammation is one of the pathophysiological causes of these diseases, the aim of this study was to determine anti-inflammatory effects of STW 5 and its components in comparison to well characterized NSAIDs such as acetylsalicylic acid and diclofenac. As a model HT-29 colon cancer cells were chosen, as it is known, that NSAIDs cause, via their inhibitory effect on COXs, an inhibition of their proliferation, as indicated by the release of lactate dehydrogenase (LDH) and by…