Neuroplasticity after Constraint Induced Movement Therapy: Patients with ipsilateral cortico-spinal organisation
N Kuhnke, H Juenger, M Walther, M Linder-Lucht, I Körte, T Hadyk, V Henschel, S Berweck, M Staudt, V Mall · Klinische Neurophysiologie · 2008 · Heft 04
Bibliografische Angaben
Zusammenfassung
Objective: Constraint induced movement therapy (CIMT) is a promising rehabilitation technique optimizing motor-learning in patients with spastic hemiparesis. Here, we describe neuroplastic effects after two weeks of CIMT in patients with ipsilateral cortico-spinal (re-)organization. Methods: 8 patients with congenital hemiparesis (mean age: 16.6 years), unilateral periventricular white matter lesions and exclusively ipsilateral cortico-spinal projections to the paretic hand were included. The Wolf motor function test (WMFT) was used to evaluate hand function before and after treatment. fMRI during repetitive act…