BPD: Regional distribution and clinical risk factors – Data from the MOSAIC trial

Aims: Bronchopulmonary dysplasia (BPD) is a major pulmonary complication of preterm birth and has been reported to occur in up to 25% of neonates below 32 weeks of gestation. Considerable local variability in the rate of BPD has been recorded. Main pathophysiological factors have been described previously: immaturity, need for mechanical ventilation and pre- and postnatal infections among others. The aims of the present study thus were to describe regional differences in the rate of BPD of very preterm neonates from 10 European regions and to delineate risk-factors obtained from this contemporary and non-selecte…