Increased liver stiffness in alcoholic liver disease: Dissecting fibrosis from steatohepatitis
S Mueller, G Millonig, S Friedrich, F Stickel, T Longerich, P Schirmacher, HK Seitz · Zeitschrift für Gastroenterologie · 2010 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims: Measurement of liver stiffness (LS) by transient elastography [Fibroscan, FS] offers a non-invasive approach to assess fibrosis stages in patients with alcoholic liver disease (ALD). However, other confounding factors in ALD such as alcoholic steatohepatitis (ASH) and cholestasis are known to strongly interfere with LS measurements. Aim of the study was to identify laboratory criteria to optimize fibrosis assessment by FS. METHODS and Results: We first performed a sequential LS analysis in 50 patients with ALD admitted for alcohol detoxification before and after normalization of serum transaminases. LS dec…
