R2* response of intracranial tumors during (C)O2 challenges at 3.0T
A Müller, S Remmele, I Wenningmann, S Flacke, R König, F Träber, H Clusmann, T Pietsch, J Gieseke, WA Willinek, HH Schild, P Mürtz · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2010 · Heft 01
Bibliografische Angaben
Zusammenfassung
Purpose: To measure and quantify changes of the R2* relaxation rate in human intracranial tumors during inhalation of carbogen and CO2/air at 3.0 Tesla. Materials and Methods: In five patients (aged 31–65 years) with intracranial tumors (1 meningioma, 2 glioblastomas, 2 metastases) the cerebral tissue response to respiratory challenges using carbogen and CO2/air was monitored with a dynamic R2* weighted multi-gradient-echo sequence of high temporal and spatial resolution. The breathing protocol consisted of 1/4/2 minutes of breathing air/gas/air, respectively. The R2* time series were analyzed voxel-wise for sig…
