EEG-vigilance in patients with cancer-related fatigue syndrome in comparison to healthy controls

Cancer related-fatigue syndrome (CFS) is a condition of severe, debilitating exhaustion and tiredness in association with malign tumors. Symptoms do not improve with sleep and sustain even years after acute stages of the malign disease or therapy interventions. While sleep disturbances seem to be related with CRF little knowledge exists about vigilance regulation in patients with CRF. For a better understanding of the neurophysiologic correlates of CFS the main aim of this study was to compare the electroencephalogram (EEG) vigilance regulation of patients with CRF with healthy controls. It was hypothesized that…