Prevalence and clinical significance of hepatitis G virus coinfection in patients with chronic hepatitis C undergoing antiviral therapy
H Hofer, I Aydin, S Neumueller-Guber, M Schoeniger-Hekele, C Mueller, C Gurguta, T Scherzer, P Steindl-Munda, F Wrba, P Ferenci · Zeitschrift für Gastroenterologie · 2008 · Heft 06
Bibliografische Angaben
Zusammenfassung
Background and Aim: Coinfection with GBV-C/HGV in patients with chronic hepatitis C (CHC) may influence clinical course and response rates of antiviral therapy with interferon/ribavirin. Aim of the study was to investigate prevalence of GBV-C/HGV/HCV coinfection and outcome of antiviral combination therapy in coinfected patients. Patients and methods: Three hundred and four patients with chronic hepatitis C (f/m=93/211, age: 42 [18–65], median[range]) were investigated. HGV RNA detection was done by polymerase chain reaction prior to initiation of interferon/ribavirin combination therapy with standard (N=111) or…
