Improved glycemic control through intensive insulin therapy in pancreatic diabetes

Background: The management of pancreatic diabetes (DM) lacks consensus, as it does not fit into either the type 1 or 2 diabetes guidelines. The aim of this study was to evaluate the effectivity of intensive insulin therapy as concerns glycemic control, body weight and safety in previously orally treated patients with DM secondary to underlying chronic pancreatitis. Methods: 13 orally treated pancreatic DM patients (10 male, 3 female, with a mean age of 57.7 (range: 47–71) years) treated with HbA1c>8% were recruited. Intensive insulin therapy was introduced instead of the oral medication, and the changes in HbA1c…