Quantitative Imaging of Angiogenesis in Defect Femoral Fracture Healing using 3D Micro- and Nano-CT
AC Langheinrich, D Kögelmaier, K Lips, V Witt, S Pacholke, C Heiß, M Kampschulte, T Hanke, R Schnettler, V Alt · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2011 · Heft 04
Bibliografische Angaben
Zusammenfassung
Ziele: To evaluate the feasibility of micro-and nano-CT for quantitative analysis of vascularization in fracture defects filled with bone substitute material. Methode: In 8 rates 5mm full-size defects were created at the left distal metaphyseal femur that was filled with silicat-collagen bone substitute material and internally fixed with plate osteosynthesis. After 6 weeks the femora were infused in situ with Microfil, harvested and scanned for micro-CT (9µm cubic voxels) and nano-CT (3µm cubic voxels) imaging. Using those 3D images, we characterized the exact size of the fracture defect and of the bone replacem…
