Molecular subtypes in medulloblastoma: an International meta-analysis for profiles, genetic aberrations, clinicopathological features AND SURVIVAL
M Kool, J Koster, M Remke, A Korshunov, T Hielscher, H Witt, P Northcott, A Schouten-van Meeteren, S Clifford, T Pietsch, A von Buehren, S Rutkowski, Y Cho, R Versteeg, C Haberler, D Ellison, R Gilbertson, S Pomeroy, F Doz, O Delattre, M Taylor, S Pfister · Klinische Pädiatrie · 2011 · Heft 11
Bibliografische Angaben
Zusammenfassung
Medulloblastoma is the most common malignant pediatric brain tumor. Already for a long time it is known that it is a very heterogeneous disease and indeed recent studies from several groups have shown that medulloblastoma comprises a collection of clinically and molecularly distinct subtypes. A better understanding of each of these molecular subtypes is now needed to improve treatment strategies and the overall survival of patients and ultimately also the quality of life for those that survive medulloblastoma. For that we have brought together all the recent molecular studies on medulloblastoma into one database…
