Ex vivo fetal membrane repair using the mussel-mimetic sealant
N Ochsenbein, C Haller, P Messersmith, E Mazza, R Zimmermann, M Ehrbar · Zeitschrift für Geburtshilfe und Neonatologie · 2011 · Heft 11
Bibliografische Angaben
Zusammenfassung
Ziel: Preterm prelabour rupture of the fetal membranes (PPROM) is an unsolved complication in pregnancy which limits the developing field of fetal surgery. The aim was to evaluate ex vivo sealing properties of a new mussel-mimetic tissue adhesive (mussel glue, MG) using punctured synthetic membranes. Methodik: Test membranes were clamped on a biomechanical test device, which by biaxial stretching permits to evaluate the mechanical properties of fetal membranes under close to physiological conditions. Synthetic membranes with 3 different thicknesses and stiffness were punctured with a punch device of 3.0mm diamet…